It is not usual to use topical antibiotics or antibiotic tablets as maintenance treatment once the spots have cleared. This is because long-term use of antibiotics can lead to resistance of germs to the antibiotics. Also, azelaic acid, another topical treatment, is only licensed for treatment periods of six months. Also, it is best not to take the pill long-term solely to prevent acne. Therefore, if at first you are treated with an antibiotic, azelaic acid or the pill, you may be advised to switch to benzoyl peroxide or a topical retinoid for maintenance treatment.
It is widely suspected that the anaerobic bacterial species Propionibacterium acnes ( P. acnes ) contributes to the development of acne, but its exact role is not well understood.  There are specific sub-strains of P. acnes associated with normal skin, and moderate or severe inflammatory acne.  It is unclear whether these undesirable strains evolve on-site or are acquired, or possibly both depending on the person. These strains have the capability of changing, perpetuating, or adapting to the abnormal cycle of inflammation, oil production, and inadequate sloughing of dead skin cells from acne pores. Infection with the parasitic mite Demodex is associated with the development of acne.   It is unclear whether eradication of the mite improves acne. 
Moderation and regularity are good things, but not everyone can sleep eight hours, eat three good meals, and drink plenty of water a day. One can, however, still control acne despite one's frantic and unpredictable routine. Probably the most useful lifestyle changes one can make is to never to pick or squeeze pimples. Playing with or popping pimples, no matter how careful and clean one is, nearly always makes bumps stay redder and bumpier longer. People often refer to redness as "scarring," but fortunately, it usually isn't permanent. It's just a mark that takes months to fade if left entirely alone.